N.B. This is a serious topic. Please stop spreading propaganda about acetaminophen being addictive or causing autism. Please read the study. The point of the study is not about acetaminophen. It is about social pain can hurt as much as physiological pain. Only people with trait of high level of forgiveness responded to acetaminophen. Acetaminophen will not work for you if you not a kind. forgiving person. No need to worry about acetaminophen if you have a weak trait. Kindness can be learned by not trolling

Social pain (psychache), such as ostracisation/rejection/bullying, can hurt as much as physical pain. Forgiveness and acetaminophen have interactive effects on experiences of social pain. Telling victims to just “let it go” is just like withholding pain medicines from patients recovering from surgery.

We need to tell the victims that psychological wounds are like physical wounds. They will heal but the healing processes can be long and painful. Psychological pain may come back in waves, and the scars may remain just like physical scars. If the psychological pain is unbearable, don’t hesitant to seek mental health. “It’s okay not to be okay.” Don’t be persuaded to think “it is all in the head.” Psychological wounds are as real as physical wounds. Good luck.

  • Sam_Bass@lemmy.world
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    12 days ago

    I hit something a little different for my depressed attitudes and it works as good as a prescribed medication. Alpha GPC

    • ryannathans@aussie.zone
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      12 days ago

      If alpha GPC (choline) works you might have methylation mutations impacting your folate metabolism. Have a look at methylfolate, b2 and methylcobalamin and maybe get your MTHFR, MTR, MTRR, COMT genes tested. The supplement trimethylglycine might do ya wonders too

      • Sam_Bass@lemmy.world
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        12 days ago

        Yeah I’m not doing any of that. Already don’t have a full deck to play with, so they could just call it that and fee me to the poorhouse for the priviledge. Alpha gpc’s main attraction is its cheap and easy to get

        • ryannathans@aussie.zone
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          12 days ago

          Alpha GPC is literally the most expensive thing on that list, those are vitamins B2, B9 and B12. You’ll probably benefit from egg yolk which contains the fat soluble version of alpha GPC (choline)

  • aarch0x40@lemmy.world
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    12 days ago

    This could also extend to acetaminophen being addictive (coping mechanism) and prone to abuse.  It’s just less likely (obvious or known) when people are physically harmed by acetaminophen toxicity.

    • Broadfern@lemmy.world
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      12 days ago

      Taking pain meds every day because you’re in otherwise unmanageable pain is not the same as taking meds every day for the high*.

      “Abusing Tylenol” isn’t a thing. There are no highs off of it, even. The problem is the cause of the pain, not the treatment.

      *High != bad, and addiction isn’t a personal failure either.

      • aarch0x40@lemmy.world
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        12 days ago

        Using anything to escape or dull an emotional state is the very root of addiction.  Just because use doesn’t result in the onset of a high doesn’t mean it can’t be used to alter a psychological state, which, is the basis of the article.  Your definition of addiction seems to be extremely narrow.  Using pain medication in place of healing emotionally fits.

        Who said addiction is personal failure?  We’re all addicted to things that make us feel better one way or another.

        • bignate31@lemmy.world
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          12 days ago

          I use water to escape the emotional state of feeling dehydrated. and I exercise to escape the emotional state of wishing I was more physically healthy.

          just throwing around the “addiction” term like this is extremely damaging to yourself and those who suffer from real addictions

    • CatDogL0ver@lemmy.worldOP
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      11 days ago

      Acetaminophen doesn’t cause addiction. Pls stop spreading propaganda. Acetaminophen doesn’t cause euphoria and there is no withdrawal.

      Spreading propaganda is addictive.

      • lightnsfw@reddthat.com
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        11 days ago

        I do get buzzed when I take acetaminophen. Just on a normal dose. Can’t speak to withdrawal or addiction as I don’t take it much to develop that but it does have an effect.

    • Tollana1234567@lemmy.today
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      12 days ago

      how are nsaid addictive? they cause significant physical damage before you can get addicted to it. you dont even get high off of nsaid.

        • MajorasTerribleFate@lemmy.zip
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          12 days ago

          Increased hangover even with less alcohol kicked in for me in my early 30s, but mine was likely due to interaction with prescribed medications I’m still on. Either way, my organs thank me.

          • spicy pancake@lemmy.zip
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            12 days ago

            yeah I’m only half mad because i have other health issues i need to be working on, i don’t need to be adding a carcinogen into the mix

            plus, all the homebrew and cocktail hipsters are also getting old, so the NA beverage industry is gaining momentum

            Seedlip and Pearson’s spirits, Asahi Zero and Athletic beer, Lyre’s cocktails, and BOLLE and French Bloom wines are some of my craft NA faves

          • spicy pancake@lemmy.zip
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            12 days ago

            Don’t think so given the hilarious quantity of gluten I eat intentionally in the form of seitan. Fuck I really hope not. Eco-friendly cheap protein does not have an abundance of varieties 💀

            I should probably do another elimination diet for a month or so to check at some point. Been a few years

            • ryannathans@aussie.zone
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              12 days ago

              That was what I thought too 🙃 then my health problems went away after I stopped lol now I get sick driving past wheat fields

              • spicy pancake@lemmy.zip
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                11 days ago

                I’m already lactose intolerant and while I’m not big mad at that because the dairy industry is rat trash anyway, if i become gluten intolerant I swear to fuck I’m gonna pull a Thought Emporium I FUCKING LOVE BREAD AND SEITAN

                • ryannathans@aussie.zone
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                  11 days ago

                  Hahaha I was lactose intolerant too! After I stopped gluten I can once again consume copious quantities of lactose without any issue. Apparently that’s a pretty common response

          • spicy pancake@lemmy.zip
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            11 days ago

            since nonalcoholic beers have gotten much better in quality and variety, i have been enjoying some lately at least

  • FoxyFerengi@startrek.website
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    12 days ago

    This is pretty funny given the recent political assertions that Tylenol causes autism, because rejection sensitive dysphoria is a symptom of autism/adhd

    • liuther9@lemmy.world
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      11 days ago

      It might be a symptom but is it the thing that occurs only in autistic people and normal people do not experience this feeling?

        • liuther9@lemmy.world
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          10 days ago

          I mean I didn’t get what you implying, are you telling that gov was right about acetaminophen and autism? The article just says that it can uplift the psychological pain with which I do agree as I have first hand experience

          • FoxyFerengi@startrek.website
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            10 days ago

            I was just making a joke :)

            Tylenol does not cause autism. Given how often people with autism experience RSD it is funny to think that an imagined cause of autism could also be a treatment for one of its symptoms

    • peoplebeproblems@midwest.social
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      12 days ago

      Wait

      I’m abnormally sensitive about rejection because of my AuADHD?

      What the flipping fuck. Fuck this shit. What drugs just turn off my brain so I can just be a blob of flesh until I die of old age since they don’t like how often I complain about existence being so goddamn difficult.

      • FoxyFerengi@startrek.website
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        12 days ago

        I hear you, I’m ND too. Reading about things like RSD being common in people like us has at least helped me be easier on myself.

        Existence is goddamn difficult and I wish I had an answer, because turning my brain off sounds wonderful. Alcohol can do that, but it comes with some awful consequences. I’ve also abused quetiapine, but eventually that fucked me up too. Weed does not play nice with my brain

        • peoplebeproblems@midwest.social
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          12 days ago

          Man quetiapine just made me panic and feel like I couldn’t breathe. Actually there are a shit ton of “sedating” medications that do that to me thinking about it.

          Except of course benzos, but thanks to those being cross tolerant with z drugs, they really gotta pump those in me to work at all.

          I’ve had a little success with clonodine.

          I remember abilify completely shut off my ability to think. Still had emotions, just no reasoning.

          People talk about Dating being this thing that’s easy to do. Yeah. Maybe if you had any choice over what was and wasn’t difficult.

          Im thinking about walking into therapy tomorrow and just asking “do I have to work if I’m just gonna be miserable anyway?”

          • FoxyFerengi@startrek.website
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            12 days ago

            I’m on clonidine for ADHD. I can actually stop myself from speaking out of turn now, so maybe it has been a little sedating xD

            Dating is kind of a nightmare. I know people say anyone can find a partner, but that doesn’t take into account things like sensory issues or hard boundaries around other things that keep us sane. I told myself a few years ago that I didn’t want to date while I’m university, but honestly it’s been so nice not forcing myself to fit into other people’s boxes that I might just stay single even after I earn my doctorate

            I’m also with you on refusing to participate in a misery machine for a living. I hope you can hash out some kind of misery escape plan with your therapist tomorrow

            • Xaphanos@lemmy.world
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              12 days ago

              I’m on a max dosage of clonidine for HBP. I didn’t know it had other effects. It does explain a bit. Thanks for the info.

      • What the flipping fuck. Fuck this shit. What drugs just turn off my brain so I can just be a blob of flesh until I die of old age since they don’t like how often I complain about existence being so goddamn difficult.

        Marijuana.

        • Angelevo@feddit.nl
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          12 days ago

          Different people react differently to molecules. In some people (I think higher prevalency in people with Autism/AD(H)D) the THC is more likely to cause psychosis.

          These things are not “one size fits all”, at all.

          • FoxyFerengi@startrek.website
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            11 days ago

            Edit: When I made this comment the person above was being unfairly down voted. What they said has scientific merit and the reader can easily verify.

      • Rooty@lemmy.world
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        12 days ago

        Sheesh, tell me about it, just about every quirk of my personality turns out to be an ADHD symptom in the end.

      • CatDogL0ver@lemmy.worldOP
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        11 days ago

        It didn’t turn off the brain. Read the study. Only people with trait of high level of forgiveness responded. In another word, nice, forgiving people.

        Are you a nice, forgiving person? It works for good people only

        • FoxyFerengi@startrek.website
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          11 days ago

          The commenter that you replied to was expressing despair at how difficult their life is because they have AuDHD. They are not saying that Tylenol can turn off their brain, they are instead asking for recommendations to escape their misery.

          You could try understanding the comment chain and comments before saying something that sounds cruel like:

          “Are you a nice, forgiving person? It works for good people only”.

          Many neurodivergent people grow up abused by their parents because of their needs, and struggle with feeling like they are not good, not good enough, and not worthy of love. Saying what you did, unprovoked, to a ND person can send someone into a self-hatred spiral that is wholly unnecessary and has nothing to do with what they actually said.

        • Angelevo@feddit.nl
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          12 days ago

          No, that would be one of the worst options. There are far better ones. Not going to advise those either though – substance dependency is not a pleasant thing for anyone.

      • Madzielle@lemmy.dbzer0.com
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        11 days ago

        Naw fuck that, I’d rather be a sloppy mess human than whatever the fuck “normal” standard addition humans are doing. Yeah, it’s difficult, but have you met folks who don’t have mental health issues? There’s like a whole three of them and they’re dead behind the eyes.

        • CatDogL0ver@lemmy.worldOP
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          11 days ago

          Have you read the study? It only work for people with trait of high level of forgiveness. In another word, nice people.

          Are you a nice person?

  • RizzRustbolt@lemmy.world
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    12 days ago

    You get deep enough into any emotion and it will start overlapping physical neurotransmitter pathways.

    Just ask anyone thats done research into schizoid personality disorder.

    • Kairos@lemmy.today
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      12 days ago

      “The part of the computer that does one thing is connected to the part of the computer that does another thing 🤯”

      Except our brains can change their wiring.

  • Drusas@fedia.io
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    12 days ago

    There is also research that shows that acetaminophen is not a particularly effective pain reliever, or at least, that it is only an effective pain reliever for a subset of the population.

    So I don’t know how much this would prove.

    • lightnsfw@reddthat.com
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      11 days ago

      It works for me it also gives me a little bit of a buzz. I usually take ibuprofen though unless it’s something bad in which case I take one of each.

    • Tollana1234567@lemmy.today
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      12 days ago

      its much weaker than the non-selective cox inhibitors, naproxen, ibuprofin or even aspirin. in managing fever and pain. its only useful in mild pain that isnt chronic and not severe pain.

  • kalkulat@lemmy.world
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    12 days ago

    Old doctor joke: Patient: “Hey Doc, it hurts when I do this.” Doc: “Quit doing that!” Same holds true of social pain. Trust yourself, stay true to yourself, avoid the pain sources, and ‘find the others’.

          • ☂️-@lemmy.ml
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            10 days ago

            no way i’m being a “better person” for people that will fuck me over as soon as i let them again.

            they be a better person for a change.

            • crapwittyname@feddit.uk
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              10 days ago

              That’s how it feels, sure. But you can’t properly control what other people do. You can control what you do.
              In situations where you’ve been fucked over, you can’t force the other person to feel guilty, try to make amends or seek your forgiveness. That would be great, but you can’t make it happen. All you can do is move on from it, which means forgiving them. If you hold a grudge, that’s mental effort, time and energy that you’re continuing to spend on them, because of the shit that they did. If you can forgive them, not only does it make you a better person, it also removes the control they have over you. It’s not exactly satisfying, but ask yourself what would be. The past isn’t going to change, and that asshole isn’t going to suddenly grow a conscience. Don’t let their actions ruin who you are by getting consumed with bitter feelings!
              I know this is kind of general, and some things are a lot harder to forgive than others, but I find it’s amazing how much easier it gets as time passes. I’ve been treated horrendously over the years and I refuse to hold a grudge. I’ve shaken hands and made jokes with past abusers, which is probably the biggest “fuck you” I could give them. They know what they did; I’m still happy and functioning. They have no power over me, and I certainly will never let them close enough to do that again.
              I know this is all a bit unsolicited on my part here, but I just recognised what you wrote as something I’ve felt too, and I would’ve liked someone to tell me this when I was. I’m not trying to preach.

              • ☂️-@lemmy.ml
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                10 days ago

                it’s fine, i enjoy relating to people’s experiences. i don’t let this kind of stuff consume me anymore though, i treat people how they act towards me. that sometimes includes not being nice.

                i draw lines on what i don’t want, and that makes me look unforgiving, but anyone can learn to be better.

                in any case i appreciate your thoughtful response.

      • zeca@lemmy.ml
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        11 days ago

        Im still wondering what the helll does it mean to have “a high level of forgiveness”

  • kerrigan778@lemmy.blahaj.zone
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    11 days ago

    This appears to be a tiny undergrad study on something neat. I think y’all are reading too much into this. Also, there appears to be no link between acetaminophen and autism but that has absolutely nothing to do with this study.