Damn, I think this is the first one (that I’ve seen) that I haven’t been able to guess and find a quote for.

My first guess was Leela and the Genestalk, which from the other comments seems incorrect.

Second was beast with a billion backs but I don’t think yivo actually leaves many suction marks mostly just “Yivo touched me in a bad place, my spinal cord!”

From the hint in the comments that they were indeed tentacle marks, I thought maybe it was a head in the polls where Fry activates the thought activated “magic tentacles” of the hotel bed, but I don’t think those leave marks and fry is wearing black in that scene not his red jacket.

The only other one I could think of was Farewell to Arms in which leela gets covered in tentacle marks from the monster in the puddle but if I recall correctly in the next scene fry is only wearing his underwear, no red jacket.

I have been beaten but as a wise old polygamist once said: “You can crush me but you can never crush my spirit! … Ahh my spirit!”

Dry eats an eg

Leela mutates into a tentacle monster.

If we really wanted to make it difficult, we could use stills from the newer episodes. I feel like most of us either haven’t seen all of them or haven’t seen them enough to know where they’d be from.

Leela and the genestalk? From Leelas tentacles when she and fry hold hands.