The Supreme Court is set to hear one of the most important trans rights cases in history on Wednesday, with the nation’s highest court set to decide whether a state-level ban on gender-affirming care for minors is an unconstitutional form of sex discrimination.

The ban in question, passed by Tennessee’s Republican-led legislature in the form of SB1, prevents doctors from prescribing puberty blockers, hormone treatment or surgery to minors experiencing gender dysphoria. The same medications can be prescribed to cisgender teens who go through puberty too early or too late, but not for those who feel uncomfortable with their assigned gender.