I’ll say that I think if the situation was truly as simple and non-nuanced as you describe, I wouldn’t have any reason to be confused or uncertain on the topic.

But as stated, since even those who adhere to best practices seem to be at higher risk with compound exposure, I think your claim of simple acclimation is a little lacking. I think there is truth in what you say, but far from the whole truth and it is what is missing which eludes me as well.