Yakko from the Animaniacs, though he may be a bit too smart for the job.

Just for the comedy that might ensue from how horrible of a president he’d be, my vote is Principal Dr. Cinnamon J. Scudworth with Buttlertron as his VP.

Either that, or if possible, as a slightly more serious answer, why not have someone like an actual scientist like Professor Professor from The Secret Show with Name Changed Daily as the VP ( or vice versa )? They already run a not-so-secret spy organization, so why not?

Satsuki Kiryuin, fuck it she might get our shit together.

Scrooge McDuck (Duck Tales version). Dude knows how to manage people and balance a budget. Sure he might occasionally get obsessed with some treasure in the middle east but that’s no different than most presidents.

Hobbes

MegaMind.

Näusicaa of the Valley of the Wind

Bill Cipher

Daria

Jesus of Nazareth

Jessica Rabbit.

All those “women can’t be president” douchebags would shut the fuck up and start becoming “nice guys” which would be cringy but at least it would get them to stop sabotaging the rest of us.

Do comic books count? If yes I’d say Spider Jerusalem from Transmetropolitan. If no, General Hunter Gathers from Venture Bros or Dale Gribble from King of the Hill. Maybe Uncle Duke from Doonesbury.